Regenerative and performance therapies have exploded across health optimization clinics. What used to be niche—IV drips, ozone, HBOT, PRP, shockwave, red light, cryo—is now increasingly expected. Patients seek out tangible improvements in energy, recovery, cognition, and long-term health, and these therapies are delivering.
But the question for you isn’t: “Which therapies should I offer?”
It’s: “Which ones actually move the needle when used intentionally, in the right sequence, for the right patient?”
This week, we break down how top integrative and longevity clinics are using these therapies within structured, data-driven programs.
The Shift: From One-Off Treatments to Regenerative Protocols
Ind of single-session inputs, the right therapies become components of multi-phase protocols addressing:
Circulatory health
Inflammation
Metabolic flexibility
Mitochondrial function
Neurological recovery
Tissue repair
This shift mirrors the way personalized medicine continues to evolve. It’s not supplements-as-menu-items. It’s root-cause protocols that are evidence-guided, personalized, and iterative.
Regenerative and Optimization Therapies To Consider at Your Clinic
As patients request these modalities, you have the opportunity to guide them toward treatment that fits their specific needs. The broader the care your practice can offer, the better you can precisely match health conditions and wellness goals with protocols.
Some of the most commonly implemented options at integrative and longevity clinics today include:
Hyperbaric oxygen therapy (HBOT): As one of the most evidence-backed tools in regenerative medicine, HBOT has moved from experimental to increasingly standard in cutting-edge practices. Recent research highlights its effects on telomere lengthening, senescent cell reduction, neuroplasticity, wound healing, stem cell mobilization, and post-concussive and cognitive recovery.
IV therapy: The value here depends entirely on context, but IV therapy can be a useful tool for certain use cases. It can help with correcting documented micronutrient deficiencies, addressing GI malabsorption, and delivering acute hydration or immune support during high-demand recovery periods for the patient (travel, intensive training, post-viral).
Ozone therapy: Controlled oxidative stress may improve circulation, modulate immunity, and stimulate mitochondrial biogenesis. Ozone therapy most often effectively applied in chronic infections, mold/mycotoxin recovery, autoimmune modulation, and fatigue syndromes.
Extracorporeal shockwave therapy (ESWT): This treatment is gaining traction not just for orthopedic use, but also vascular and sexual health applications. Shockwaves can help to increase blood flow, break down scar tissue, stimulate fibroblast activity, and reduce chronic pain patterns.
Platelet-rich plasma (PRP) + ESWT: Some clinics apply ESWT and PRP together for a one-two regenerative punch, complete with growth factors, collagen remodeling, and accelerated repair. This allows clinicians to help patients with tendinopathy, chronic soft-tissue injuries, erectile dysfunction (vasculogenic), pelvic floor and postpartum recovery, fascia and ligament support, and vascular optimization programs.
For many of these therapies, the evidence is still emerging. Still, patient-reported outcomes can be meaningful, especially when paired with appropriate monitoring.
The difference lies in moving away from one-size-fits-all, one-off wellness menus to personalized and closely tracked applications. With lab correlation and patient-reported changes, you help these therapies deliver actual results.
Leveling Up: Matching Therapies to Patient Goals
You can go beyond musculoskeletal support and care for acute and chronic conditions. The leading functional, integrative, and longevity clinics use personalized protocols to provide full-spectrum care.
You might, for example, apply these leading-edge treatments to help patients with their priorities like:
Sexual health: Here, patients may see improvement with some combination of shockwave + PRP, peptides, hormone optimization, pelvic floor rehab, and vascular interventions.
Cognitive performance: To support their mental acuity, you might deploy HBOT, red light therapy (near-infrared [NIR]), ketone esters, mitochondrial support, and/or structured sleep optimization.
Metabolic enhancement: Care here could include GLP-1s with supervised off-ramping, sauna+cold cycles, resistance training integrated with CGM insights, and mitochondrial peptide research.
Recovery: Personalize the recovery stack to the patient. It might include red light therapy (photobiomodulation [PBM]), heat stress through saunas, pulsed electromagnetic field (PEMF) therapy, compression/lymphatic therapy, and/or cryotherapy/cold exposure.
Most “wellness therapies” deliver incremental gains alone, but exponential gains when integrated into a clinical protocol. That’s where the real power to move the needle lies.
Developing these programs and applying them to the individual patient represents the shift toward function-first health, where outcomes are measured across multiple physiologic systems.
📙 Your Homework: Build a Regenerative Protocol Instead of a Menu
Choose one patient on your schedule this week with any of the following:
Chronic inflammation
Chronic pain
Post-viral fatigue
Sexual health concerns
Cognitive decline
Slow recovery or metabolic dysfunction
Create a 4–6 week regenerative protocol using:
Foundational Support → Optimize nutrition, movement, sleep, and targeted mitochondrial supplements.
Primary Pillar → Apply one core therapy (HBOT, ESWT+PRP, IV support, or red light).
Recovery Accelerator → Add sauna, cryo, PEMF, or compression to enhance repair and resilience.
Follow‑Up Assessment → Measure subjective outcomes and objective biomarkers at 4–6 weeks.
This moves the patient from trying scattered interventions to participating in a structured, measurable program.
That shift—from modalities to outcomes—is what defines a high-performing modern clinic.
How I AI with Sunjya Schweig
This week, we sat down with Sunjya Schweig, MD, founder and president of both the California Center for Functional Medicine (CCFM) and the Functional Medicine Research and Technology Center.
Dr. Schweig has over 25 years of functional and integrative medicine experience, and he’s expanding how he applies that expertise through AI. He and his team are bullish on AI for a simple reason: the gains are real, and growing. In our conversation, he walked through the ways he’s already using AI in practice — and how he guides patients who bring AI into the room with them.
Some of the highlights from our conversation:
Use patient-generated AI as a starting point. Some patients upload their entire medical record into ChatGPT or Perplexity before visits. While his practice stays HIPAA-compliant, Dr. Schweig treats these summaries as useful signals instead of threats. He uses them to quickly see what patients think is important, identify misconceptions, and guide deeper conversation.
Try this: Ask patients, “What did your AI tell you that you’re unsure about?” It surfaces misunderstandings immediately.
Keep “doctor in the loop” when AI is wrong. One patient even named her ChatGPT “Jerry.” Sometimes Jerry was wrong. Dr. Schweig validates her initiative, corrects inaccuracies, and reinforces that AI can support—but never replace—clinical judgment.
Try this: Use a simple redirect such as, “Let’s look at what this got right, and where medical nuance matters.”
Cross-check with multiple models. Dr. Schweig often runs the same query through two different LLMs. He researches with one model, then runs that output through another to evaluate reasoning or missing risk factors before applying it clinically.
Try this: Use an “LLM-as-judge” prompt like: “Review the following output and identify gaps, risks, or misleading statements.”
Build small AI tools that extend care. He created a custom GPT to teach proper form for basic bodyweight exercises and experiments with lightweight tools for patient education. These save time, standardize guidance, and improve follow-through between visits.
Try this: Build a micro-GPT for one repetitive education topic (sleep hygiene, elimination diet basics, posture) and personalize the final details during the visit.
The takeaway
AI isn’t replacing physician judgment. It’s expanding it: helping clinicians understand patients more deeply, cross-check information efficiently, and deliver education at scale.
Dr. Schweig’s philosophy:
You can put artificial intelligence behind your team with Vibrant, the AI-powered, all-in-one practice platform. Schedule some time with our team to learn more.
This Week in Clinical AI
More than 16% of American adults regularly use chatbots to find medical information. For folks under 30, that percentage ticks up to roughly 25%. In interviews with The New York Times, people reported turning to chatbots to overcome shortcomings in the healthcare they’ve traditionally received. As The Times’s article title says, chatbots can be helpful health tools because they’re “empathetic, available, cheap.”
Last week’s Eudēmonia Summit draws more than 5,000. The three-day summit focusing on “wellness, longevity, and human potential” wrapped up its second annual event. In addition to wellness activities ranging from breathwork workshops to HBOT and more than 270 expert-led talks, this year’s event featured the new Health Innovation Lab. There, founders, investors, and health pioneers discussed the future of leading-edge medicine.
Function Health announces $298 million in new funding. The startup currently uses peoples’ lab tests and body scans to personalize health guidance (e.g., nutrition recommendations, specific supplements, lifestyle modifications). With the new round of funding secured, the company plans to add AI features that help to interpret the data that comes in from each individual.
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