
Every clinician has a signature method for making sense of complexity—how labs are contextualized, how symptoms cluster, how risk is evaluated, and how a care plan takes shape. This reasoning is the true intellectual capital of a practice. Yet in most clinics, it lives in scattered places: PDFs, EHR templates, team messages, notebooks, and memory. Valuable, but invisible.
A clinical knowledge graph makes that internal reasoning visible. It organizes how you think. How you interpret information, how you prioritize steps, and how your approach adapts as new clinical data emerges. Instead of fragmented documents, you create a clear, consistent framework for your team.
This structure enhances quality, clarity, and consistency across the clinic, helping every team member understand your philosophy of care. Even when you cannot be in a million places at once. It also supports the creation of patient-facing education, training materials, and communication templates that reflect your standards and protect the integrity of your clinical voice.
As AI tools increasingly support administrative tasks such as organizing information, drafting summaries, or structuring educational content, your knowledge graph provides the context and guardrails required to keep these tools aligned with your clinical approach. Human oversight remains essential at every step—AI does not diagnose, treat, or replace clinical decision-making.
Why It Matters Now
Large language models can summarize information, but they cannot reflect your professional judgment or individual approach unless you make that reasoning explicit. Without your interpretation ranges, red-flag thresholds, priorities, or sequencing, AI tools default to generic explanations that don’t reflect your care philosophy.
A clinical knowledge graph becomes a source of consistency for your entire practice by:
Reducing variation across providers
Creating predictable, high-quality patient experiences
Improving handoffs and documentation clarity
Supporting compliant educational materials and templates
Ensuring that any AI-assisted outputs stay anchored in your clinical framework—with full human review
This is how modern practices scale without compromising quality.
What Goes Into Your Clinical Reasoning Map
Interpretive frameworks
How you read labs and symptoms in context; thresholds that shift your differential or next steps.
Clinical sequencing
The order you address issues and why; what must stabilize before moving forward.
Pattern recognition
Common presentations you see repeatedly; clues that shift your clinical pathway.
Practice rules & safety checks
Your everyday “if X, check Y” habits; red flags and monitoring intervals.
Decision points
When you escalate, simplify, order diagnostics, or refer—all with human clinical judgment at the center.
This structure helps AI tools organize information and draft materials, not make decisions. Clinicians remain fully responsible for interpretation and care.
Example: Perimenopause
A static protocol may list sleep support, strength training, and hormone therapy—but your knowledge graph captures the reasoning behind each step.
It reveals:
Why sleep must stabilize before HRT
Which phenotypes need metabolic work first
How trauma history shapes pacing
How alcohol, CGM, or cortisol patterns shift the plan
What to monitor weekly vs. monthly
Where botanicals or lifestyle tools fit across symptom clusters
What this produces: clear care pathways, consistent team communication, and high-quality patient education.
Patient impact: smoother treatment progression, fewer mixed messages, and a care experience that feels coordinated, personalized, and easier to follow.
📙 Your Homework: Make Your Clinical Reasoning Visible
Choose one condition you manage often (fatigue, perimenopause, IBS, insulin resistance, migraine).
Document your approach using a format that works for you:
Voice mode on ChatGPT (for drafting educational or organizational materials only)
A hand-drawn diagram uploaded as a photo
A simple document in Notes, Notion, or Google Docs
Think of it as teaching a resident: “Here’s how I typically think through this clinical picture.”
1. List the clinical clues you always scan. Energy patterns, sleep, cycles, ferritin, CGM trends, inflammation markers, symptom timing.
2. Capture your interpretation habits. Values that get your attention; combinations that shift your thinking.
3. Outline your usual order of operations.
What you stabilize first, when you escalate, and the markers of readiness for the next step.
4. Write down your rules of thumb. Common “clinical sayings” that guide your day-to-day reasoning.
5. Keep it easy to update. A simple document or sketch is enough.
6. Test it with one de-identified case. Use an AI tool only to check whether your framework is communicated clearly, not to make clinical decisions.
Human oversight remains required in all clinical contexts.
What You’re Actually Building
Your clinical style—made visible.
A tool for consistency, team alignment, and reduced cognitive load.
A stable foundation for patient education and clinic-wide communication.
So handouts, summaries, and onboarding materials reflect your professional judgment.
A reference point for AI-assisted drafting (with human review).
Ensuring that summaries and educational content remain aligned with your philosophy—not generic guidelines.
The Takeaway
When clinicians make their reasoning visible, three things happen:
Care becomes more consistent across the entire team
Patient education improves without additional strain on the clinician
AI-assisted materials remain safe, grounded, and clinically aligned—always with human oversight
This is not a new skill. It is simply the next step in documenting and scaling the expertise you already use every day—without ever replacing the clinician.
How I AI with Dr. Lexi Gonzales
Using NotebookLM to Turn Staff Training Into a Living Knowledge Base
Dr. Alexis (Lexi) Gonzales has been exploring one of the most surprisingly high-leverage uses of AI inside a modern clinic: transforming staff training from static PDFs into an interactive, always-up-to-date knowledge system. Instead of repeating explanations, rewriting SOPs, or answering the same questions from every new hire, she uses NotebookLM to centralize all training materials and make them conversational. Staff can ask questions, clarify concepts, and learn at their own pace—all grounded in the exact source material Lexi has uploaded.
What makes this powerful is NotebookLM’s retrieval-based design. Unlike ChatGPT, which can drift or forget context, NotebookLM stays anchored to the documents, videos, and protocols you feed it. For clinics that roll out new tests, new technology, or updated concierge offerings, this means staff training becomes faster, more consistent, and far less dependent on clinician face time. As Lexi put it, “It’s like giving your team shared access to the same brain.”
How She Uses It
1. Centralize every piece of training material. SOPs, ordering instructions, manufacturer PDFs, YouTube explainers, even onboarding videos—all go into a single NotebookLM “notebook.”
2. Let staff “chat” with the information. Instead of re-reading long SOPs, team members ask:
“Explain this test in patient-friendly language.”
“What are the newest updates?”
“What’s the difference between these markers?”
This turns passive reading into active learning.
3. Keep everything in sync automatically. When Lexi updates an SOP in Google Drive, NotebookLM reflects it instantly. Staff simply ask, “What’s changed recently?” and get the right answer—no retraining meetings needed.
Why It Works
Shared language across the whole team. Front desk, MA, nurse, and virtual staff can all speak confidently about tests, programs, and protocols—without relying on the clinician to fill gaps.
Faster onboarding with less clinician time. The knowledge graph does most of the teaching. Lexi steps in only for nuance.
Scales to anything new. New diagnostics, new programs, new technologies—anything that requires staff competence can be uploaded, explored, and mastered the same way.
Try This
Pick one area your team constantly asks about—microbiome testing, membership benefits, hormone panels, or supplement rules.
Upload every relevant document into NotebookLM.
Then have your team ask it the questions they usually bring to you.
You’ll feel the leverage immediately.
You can streamline your team’s clinical and operational workflows with Vibrant, the AI-powered, all-in-one practice platform. Schedule some time with our team to learn more.
This Week in Clinical AI
Cerbo and OptiMantra announce merger under incoming CEO Jeff Hindman. Two major practice-management and EHR platforms are joining forces to streamline operations for integrative and functional medicine clinics. The merger aims to consolidate technical infrastructure and accelerate product innovation across scheduling, charting, and patient engagement tools. For clinicians, this signals a potential shift toward more unified, interoperable systems—particularly valuable as AI-enabled workflows grow and require cleaner, more structured data inputs.
Nature publishes the inaugural editorial from Nature Digital Medicine, spotlighting the future of clinical AI regulation and evidence standards. The launch issue emphasizes the need for transparent evaluation frameworks as AI agents begin performing increasingly autonomous tasks in clinical workflows. The editors call for rigorous methodologies, reproducibility standards, and clearer definitions of “clinically validated” vs. “clinically useful.” The piece underscores a growing consensus: AI’s trajectory in medicine now depends on trust, safety, and implementation science just as much as technical capability.
NEJM AI analyzes the emergence of agentic AI systems in healthcare. A new NEJM AI paper outlines how agentic systems—models capable of planning, taking multi-step actions, and interacting with clinical tools—will reshape everything from documentation to triage to care pathway recommendations. The authors highlight both the upside (workflow acceleration, reduced cognitive load, real-time synthesis) and the risk (opaque reasoning, variable reliability, and the need for guardrails). For clinics preparing for the next wave of AI adoption, this piece offers one of the clearest roadmaps to date.
A new company enters the race toward gene-edited babies. MIT Technology Review reports on the latest startup working to commercialize germline gene editing for reproductive use—reviving global debate on ethics, regulation, and equity. While still speculative, the company claims it can reduce off-target effects and improve editing precision. For clinicians, the story signals a broader shift: advanced reproductive technologies are accelerating faster than governance frameworks, demanding thoughtful clinical, ethical, and public-health conversations.
👋 Welcome New Readers
The Modern Clinician is written for functional, integrative, and longevity-focused physicians who want to scale their impact and deliver cutting-edge care.
If you liked this one, share it with a colleague! We appreciate you spreading the word.
To learn more about the why behind this newsletter, start with our first post introducing The Modern Clinician.